Acute Systemic Toxicity

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Local Anesthetic Systemic Toxicity.

Local anesthetics are commonly used in the perioperative environment to facilitate surgical procedures or to provide postoperative pain management for patients. The use of local anesthetics, however, introduces the risk of complications resulting from local anesthetic systemic toxicity and the risks of increased morbidity and mortality for the surgical patient. Systemic toxicity from the inject...

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Local anesthetic systemic toxicity.

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Local Anesthetics Systemic Toxicity.

Lidocaine Hydrochloride is an amide ester, which is widely used local anesthetic agent that is well tolerated but what is less known is the occurrence of systemic toxicity which manifests in the central nervous and cardiovascular systems. We report here 3 cases of Lidocaine associated Seizures.

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Systemic toxicity of paraphenylenediamine.

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1. Inventory of methods currently available From the regulatory point of view, the main objective of acute toxicity testing is basically to classify chemicals according to their intrinsic toxicity as required by the EEC directive on classification, packaging, and labelling of dangerous substances (Council Directive 67/548/EEC and subsequent amendments). This requirement aims to protect public h...

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ژورنال

عنوان ژورنال: ILAR Journal

سال: 2002

ISSN: 1930-6180,1084-2020

DOI: 10.1093/ilar.43.suppl_1.s27